Tag Archives: Disease

Outbreak of hantavirus infections kills three in Washington state

A micrographic study of liver tissue seen from a Hantavirus pulmonary syndrome (HPS) patient seen in this undated photo obtained by Reuters, July 6, 2017. Centers for Disease Control and Prevention/Handout via REUTERS

By Laura Zuckerman

(Reuters) – Five people have been stricken with the rare, rodent-borne hantavirus illness in Washington state since February, three of whom have died, in the state’s worst outbreak of the disease in at least 18 years, public health officials reported on Thursday.

The three fatal cases also mark the highest death toll from hantavirus pulmonary syndrome in Washington state during a single year since the respiratory ailment was first identified in the “Four Corners” region of the U.S. Southwest in 1993.

The disease has been found to be transmitted to humans from deer mice, either through contact with urine, droppings, saliva or nesting materials of infected rodents or by inhaling dust contaminated with the virus.

Victims in the latest outbreak were men and women ranging in age from their 20s to their 50s from four counties across the state, said David Johnson, spokesman for the Washington State Department of Health.

The first diagnosed case this year was in February and the most recent was last month, when the infection killed a resident of Spokane County in the eastern part of the state near Washington’s border with Idaho. Three of the five cases, including another one that proved fatal, were confirmed in the Puget Sound region of King and Skagit counties.

The only common factor among those infected by the disease, which typically kills more than a third of its victims, is that they were all exposed to infected mice, Johnson said.

The last time five confirmed hantavirus cases were diagnosed in Washington state in a single year was in 1999, although just one of those proved fatal, Johnson said.

Washington has reported 49 of the 690 hantavirus cases tallied nationwide from 1993 to January 2016, ranking fifth among 10 Western states that account for the bulk of all documented infections, according to the federal Centers for Disease Control and Prevention (CDC) in Atlanta.

Eighteen infections with four deaths were reported nationally in 2015. The year before, the CDC counted 35 cases, of which 14 were fatal.

The most highly publicized hantavirus outbreak occurred in 2012, when 10 visitors to Yosemite National Park in California were diagnosed with the infection, three of whom died, prompting a worldwide alert. All but one of those were linked to tent cabins later found to have been infested by deer mice.

(Editing by Steve Gorman; Editing by Paul Tait)

Yemen’s cholera death toll rises to 1,500: WHO

FILE PHOTO: Women sit with relatives infected with cholera at a hospital in the Red Sea port city of Hodeidah, Yemen May 14, 2017. REUTERS/Abduljabbar Zeyad

ADEN (Reuters) – The death toll from a major cholera outbreak in Yemen has risen to 1,500, Nevio Zagaria, the World Health Organization’s (WHO) representative in Yemen, said on Saturday, and appealed for more help to put an end to the epidemic.

Yemen has been devastated by a 27-month war between a Saudi-led coalition and the armed Iran-aligned Houthi group, making it a breeding ground for the disease, which spreads by faeces getting into food or water and thrives in places with poor sanitation.

Speaking at a joint news conference with representatives of the United Nations Children Fund (UNICEF) and the World Bank, Zagaria said that had been some 246,000 suspected cases in the period to June 30.

The WHO said this week that the outbreak had reached the halfway mark at 218,798 cases as a massive emergency response has begun to curb its spread two months into the epidemic.

Although most of Yemen’s health infrastructure has broken down and health workers have not been paid for more than six months, the WHO is paying “incentives” to doctors, nurses, cleaners and paramedics to staff an emergency cholera network.

With funding help from the World Bank, the WHO is setting up treatment centers with 50-60 beds each, overseen by shifts of about 14 staff working around the clock. The aim is to reach 5,000 beds in total.

(Reporting by Mohammed Mukhashaf, writing by Sami Aboudi; editing by Jason Neely)

Polio outbreak in Syria poses vaccination dilemma for WHO

A health worker administers polio vaccination to a child in Raqqa, eastern Syria November 18, 2013. REUTERS/Nour Fourat

GENEVA (Reuters) – Vaccinating too few children in Syria against polio because the six-year-old war there makes it difficult to reach them risks causing more cases in the future, the World Health Organization (WHO) said on Friday, posing a dilemma after a recent outbreak.

Two children have been paralyzed in the last few months in Islamic State-held Deir al-Zor in the first polio cases in Syria since 2014 and in the same eastern province bordering Iraq where a different strain caused 36 cases in 2013-2014.

Vaccinating even 50 percent of the estimated 90,000 children aged under 5 in the Mayadin area of Deir al-Zor would probably not be enough to stop the outbreak and might actually sow the seeds for the next outbreak, WHO’s Oliver Rosenbauer said.

Immunisation rates need to be closer to 80 percent to have maximum effect and protect a population, he told a briefing.

“Are we concerned that we’re in fact going to be seeding further future polio vaccine-derived outbreaks? … Absolutely, that is a concern. And that is why this vaccine must be used judiciously and to try to ensure the highest level of coverage,” Rosenbauer said.

“This is kind of what has become known as the OPV, the oral polio vaccine paradox,” he said.

The new cases are a vaccine-derived poliovirus type 2, a rare type which can emerge in under-immunised communities after mutating from strains contained in the oral polio vaccine.

“Such vaccine-derived strains tend to be less dangerous than wild polio virus strains, they tend to cause less cases, they tend not to travel so easily geographically. That’s all kind of the silver lining and should play in our favor operationally,” he said.

All polio strains can paralyze within hours.

Syria is one of the last remaining pockets of the virus worldwide. The virus remains endemic in Afghanistan and Pakistan.

(Reporting by Stephanie Nebehay; Editing by Louise Ireland)

Puerto Rico declares Zika outbreak over, CDC maintains travel warning

Aedes aegypti mosquitoes are seen at the Laboratory of Entomology and Ecology of the Dengue Branch of the U.S. Centers for Disease Control and Prevention in San Juan, Puerto Rico, March 6, 2016. REUTERS/Alvin Baez/File Photo

By Julie Steenhuysen

(Reuters) – Puerto Rico on Monday declared that the 2016 Zika epidemic is over, saying transmission of the virus that can cause birth defects when pregnant women are exposed has fallen significantly.

About 10 cases of the mosquito-borne disease have been reported in each four-week period since April 2017, down from more than 8,000 cases reported in a four-week period at the peak of the epidemic in August 2016, the Puerto Rico Health Department said in a statement.

The U.S. Centers for Disease Control and Prevention, however, has not changed its travel advice, noting that pregnant women should not travel to Puerto Rico.

The CDC said its travel notice for Puerto Rico remains in place and that it expects the virus will continue to “circulate indefinitely” in most regions where it has been introduced.

The Department of Health and Human Services declaration of a public health emergency in Puerto Rico relating to pregnant women and children born to women with the virus remains in effect, the CDC said in an emailed statement on Tuesday.

On its website, the CDC cites public health reports saying that “mosquitoes in Puerto Rico are infected with Zika virus and are spreading it to people.”

CDC acting Director Dr. Anne Schuchat said in a statement that she is “pleased that the peak of the Zika outbreak in Puerto Rico has come to a close.” However, she said, “We cannot let our guard down.”

Schuchat said CDC will continue to focus on protecting pregnant women and work closely with the Puerto Rican health department to support Zika surveillance and prevention efforts on the island, which is a U.S. territory.

A major outbreak of Zika began in Brazil in 2015 and spread rapidly to dozens of countries. There is no treatment for Zika, but private companies and governments are working on a vaccine.

In addition to Puerto Rico, the CDC has warned of a risk of Zika infection for travelers going to Mexico, Cuba, most of the Caribbean and South America, as well as parts of Africa and Southeast Asia. http://bit.ly/2m50Lf7

Locally transmitted Zika cases have also been reported in Texas and Florida.

(Reporting by Julie Steenhuysen in Chicago; Editing by Lisa Shumaker and Jonathan Oatis)

WHO says India reports cases of Zika virus

FILE PHOTO: Aedes aegypti mosquitoes are seen inside Oxitec laboratory in Campinas, Brazil, on February 2, 2016. REUTERS/Paulo Whitaker/File Photo

NEW DELHI (Reuters) – India has reported cases of the Zika virus, the World Health Organization said, adding that efforts should be made to strengthen surveillance.

The WHO said that on May 15 India’s health ministry reported three confirmed cases from the western state of Gujarat. Cases were detected during testing in February and November last year, while one was detected in January this year, according to the statement, which was released on Friday but did not gain public attention until Saturday.

A federal health ministry official said states were following standard protocols and there was “nothing to worry” about. The ministry had in March cited one confirmed case of Zika – from January of this year in Gujarat – while answering a question in India’s parliament.

“These findings suggest low level transmission of Zika virus and new cases may occur in the future,” the WHO said in the statement on its website.

“Zika virus is known to be circulating in South-East Asia Region and these findings do not change the global risk assessment.”

In its most recent outbreak, Zika, which is mainly a mosquito-borne disease, was identified in Brazil in 2015 and has been spreading globally.

When the virus infects a pregnant woman, it can cause a variety of birth defects including microcephaly, where the baby’s head is abnormally small.

(Reporting by Aditya Kalra; Editing by Tom Lasseter and Andrew Bolton)

U.S. Alzheimer’s deaths jump 54 percent; many increasingly dying at home

A healthy brain compared to a brain affected by a severe case of Alzheimer's Disease. Courtesy of Wikimedia Commons

By Julie Steenhuysen

CHICAGO (Reuters) – U.S. deaths from Alzheimer’s disease rose by more than 50 percent from 1999 to 2014, and rates are expected to continue to rise, reflecting the nation’s aging population and increasing life expectancy, American researchers said on Thursday.

In addition, a larger proportion of people with Alzheimer’s are dying at home rather than a medical facility, according to the report released by the U.S. Centers for Disease Control and Prevention (CDC).

Alzheimer’s is the sixth-leading cause of death in the United States, accounting for 3.6 percent of all deaths in 2014, the report said.

Researchers have long predicted increased cases of Alzheimer’s as more of the nation’s baby boom generation passes the age of 65, putting them at higher risk for the age-related disease. The number of U.S. residents aged 65 and older living with Alzheimer’s is expected to nearly triple to 13.8 million by 2050.

There is no cure for Alzheimer’s, a fatal brain disease that slowly robs its victims of the ability to think and care for themselves.

According to the report by researchers at the CDC and Georgia State University, 93,541 people died from Alzheimer’s in the United States in 2014, a 54.5 percent increase compared with 1999.

During that period, the percentage of people who died from Alzheimer’s in a medical facility fell by more than half to 6.6 percent in 2014, from 14.7 percent in 1999.

Meanwhile, the number of people with Alzheimer’s who died at home increased to 24.9 percent in 2014, from 13.9 percent in 1999, researchers reported in the CDC’s weekly report on death and disease.

The sharp increase in Alzheimer’s deaths coupled with the rising number of people with Alzheimer’s dying at home have likely added to the burden on family members and others struggling to care for their stricken family members, they said.

The report suggests these individuals would benefit from services such as respite care and case management to ease the burden of caring for a person with Alzheimer’s.

Alzheimer’s is the leading cause of dementia and affects 5.5 million adults in the United States. It is expected to affect 13.8 million U.S. adults over 65 by the year 2050.

(Reporting by Julie Steenhuysen)

Scientists to test whether Zika can kill brain cancer cells

FILE PHOTO - Genetically modified male Aedes aegypti mosquitoes are pictured at Oxitec factory in Piracicaba, Brazil, October 26, 2016. REUTERS/Paulo Whitaker

By Kate Kelland

LONDON (Reuters) – Scientists in Britain plan to harness the Zika virus to try to kill brain tumor cells in experiments that they say could lead to new ways to fight an aggressive type of cancer.

The research will focus on glioblastoma, the most common form of brain cancer, which has a five-year survival rate of barely 5 percent.

Zika causes severe disability in babies by attacking developing stem cells in the brain – but in adults, whose brains are fully formed, it often causes no more than mild flu-like symptoms.

In glioblastoma, the cancer cells are similar to those in the developing brain, suggesting that the virus could be used to target them while sparing normal adult brain tissue.

Experts say existing treatments have to be given at low doses to avoid damaging healthy tissue.

Researchers led by Harry Bulstrode at Cambridge University will use tumor cells in the lab and in mice to assess Zika’s potential.

The mosquito-borne virus has spread to more than 60 countries and territories in a global outbreak that was first identified in Brazil in 2015.

“Zika virus infection in babies and children is a major global health concern, and the focus has been to discover more about the virus to find new possible treatments,” Bulstrode said in a statement.

“We’re taking a different approach, and want to use these new insights to see if the virus can be unleashed against one of the hardest-to-treat cancers …

“We hope to show that the Zika virus can slow down brain tumor growth in tests in the lab,” Bulstrode added. “If we can learn lessons from Zika’s ability to cross the blood-brain barrier and target brain stem cells selectively, we could be holding the key to future treatments.”

(Editing by Louise Ireland and Kevin Liffey)

WHO confirms second Ebola case in Congo outbreak

FILE PHOTO: A health worker sprays a colleague with disinfectant during a training session for Congolese health workers to deal with Ebola virus in Kinshasa October 21, 2014. REUTERS/Media Coulibaly

By Aaron Ross

KINSHASA (Reuters) – The World Health Organization (WHO) confirmed on Sunday a second case of Ebola in Democratic Republic of Congo after an outbreak this week of 17 other suspected cases.

Health officials are trying to trace 125 people thought to be linked to the cases identified in the remote northeastern province of Bas-Uele province in northeastern Congo near the border with Central African Republic, WHO’s Congo spokesman Eugene Kabambi said.

Three people have so far died among the 19 suspected and confirmed cases, he added.

It was not immediately clear how the first victim, a deceased male, caught the virus, although past outbreaks have been linked to contact with infected bush meat such as apes.

The outbreak comes just a year after the end of an epidemic in West Africa killed more than 11,300 people mostly in Guinea, Sierra Leone and Liberia.

However, Congo, whose dense forests contain the River Ebola near where the disease was first detected in 1976, has experienced many outbreaks and has mostly succeeded in containing them without large-scale loss of life.

The GAVI global vaccine alliance said on Friday some 300,000 emergency doses of an Ebola vaccine developed by Merck <MRK.N> could be available in case of a large-scale outbreak and that it stood ready to support the Congo government on the matter.

(Reporting by Aaron Ross; Writing by Emma Farge; Editing by Louise Ireland and Gareth Jones)

U.S. suspends aid to Kenyan health ministry over corruption concerns

FILE PHOTO: A riot policeman stands guard as doctors chant slogans after their case to demand fulfilment of a 2013 agreement between their union and the government that would raise their pay and improve working conditions, was heard at the employment and labour relations courts in Nairobi, Kenya, February 13, 2017. REUTERS/Thomas Mukoya/File Photo

By Katharine Houreld

NAIROBI (Reuters) – The U.S. government has suspended $21 million in direct aid to Kenya’s Ministry of Health amid concern over corruption, the embassy said on Tuesday, giving emphasis to an issue that is a growing liability for the government before August elections.

Support for HIV drugs and other health programs outside the ministry would continue, the embassy said, adding that the United States invests more than $650 million on health in Kenya annually.

“We took this step because of ongoing concern about reports of corruption and weak accounting procedures at the Ministry,” the statement from the embassy said. “We are working with the Ministry on ways to improve accounting and internal controls.”

The announcement adds weight to a rising number of scandals plaguing the government of President Uhuru Kenyatta, who is seeking a second and final five-year term in presidential, parliamentary and local elections on Aug. 8.

The so-called Afya House scandal, named after the building housing the Ministry of Health, was based on an audit report leaked to Kenyan media in October.

The audit showed the ministry could not account for 5 billion Kenyan shillings ($49 million) and funds meant for free maternity care had been diverted, newspapers reported.

Officials at Kenya’s anti-corruption commission did not return calls seeking comment on Tuesday, but the ministry of health issued a statement.

“The ministry has been raising matters raised in the internal audit investigations following the Quality Assurance audit by the National Treasury,” the statement said.

“Other autonomous institutions … are undertaking independent investigations.”

Last year, Kenya’s anti-graft chief told Reuters that a third of its state budget – the equivalent of about $6 billion – was lost to corruption every year.

The government disputed the figure, blaming poor paperwork. In October, Kenyatta infuriated voters by telling them he could not tackle corruption because his “hands were tied”. He criticized the judiciary and other agencies for not doing more about the problem.

Kenyan doctors and nurses say the corruption means that hospitals are often left without basic equipment, from drugs to gloves. Kenyan doctors in public hospitals went on strike from December to March, demanding a pay increase and improved working conditions.

(Editing by Larry King)

Infant mortality and malaria soar in Venezuela, according to government data

Pregnant women lay on beds without sheets during their labour at a maternity hospital in Maracaibo, Venezuela June 19, 2015. REUTERS/Isaac Urrutia

By Alexandra Ulmer

CARACAS (Reuters) – Venezuela’s infant mortality rose 30 percent last year, maternal mortality shot up 65 percent and cases of malaria jumped 76 percent, according to government data, sharp increases reflecting how the country’s deep economic crisis has hammered at citizens’ health.

The statistics, issued on the ministry’s website after nearly two years of data silence from President Nicolas Maduro’s leftist government, also showed a jump in illnesses such as diphtheria and Zika. It was not immediately clear when the ministry posted the data, although local media reported on the statistics on Tuesday.

Recession and currency controls in the oil-exporting South American nation have slashed both local production and imports of foreign goods, and Venezuelans are facing shortages of everything from rice to vaccines. The opposition has organized weeks of protests against Maduro, accusing him of dictatorial rule and calling for elections.

In the health sector, doctors have emigrated in droves and patients have to settle for second-rate treatment or none at all. A leading pharmaceutical association has said roughly 85 percent of medicines are running short. Venezuelans often barter medicine, post pleas on social media, travel to neighboring countries if they can afford it, or line up for hours at pharmacies.

The Health Ministry had stopped releasing figures after July 2015, amid a wider data blackout. It was not clear why it published this latest batch of data.

Its statistics for 2016 showed infant mortality, or death of children aged 0-1, climbed 30.12 percent to 11,466 cases last year. The report cited neonatal sepsis, pneumonia, respiratory distress syndrome, and prematurity as the main causes.

Hospitals often lack basic equipment like incubators, and pregnant women are struggling to eat well, including taking folic acid, factors that can affect a baby’s health.

(To read the story on Venezuelan women seeking sterilizations as crisis sours child-rearing, click http://www.reuters.com/article/us-venezuela-sterilizations-idUSKCN10E1NK)

Maternal mortality, or death while pregnant or within 42 days of the end of a pregnancy, was also up, rising 65.79 percent to 756 deaths, the report said.

The Health Ministry did not respond to a request for further information. Maduro’s government says a coup-mongering elite is hoarding medicines to stoke unrest.

‘TURMOIL’

While Venezuelans are acutely aware of the country’s health issues, the ministry’s statistics bulletin shocked some in the medical community.

“The striking part is turmoil in almost all the categories that this bulletin addresses, with particularly significant increases in the infant and maternal health categories,” said Dr. Julio Castro, an infectious disease specialist and an outspoken critic of the government’s health policies.

Doctors say the health bulletins, meant to be released weekly, should be published in a timely fashion to alert medical practitioners to national trends and threats.

Venezuela, for instance, had controlled diphtheria, a bacterial infection that is fatal in 5 to 10 percent of cases, in the 1990s. Doctors last year sounded the alarm that it had returned, but the government initially said there were no proven cases and admonished those seeking to spread “panic.”

The data now shows diphtheria affected 324 people – up from no cases the previous year.

Diphtheria was once a major global cause of child death but is now increasingly rare thanks to immunizations, and its return showed how vulnerable the country is to health risks.

Reuters documented the case of a 9-year-old girl, Eliannys Vivas, who died of diphtheria earlier this year after being misdiagnosed with asthma, in part because there were no instruments to examine her throat, and shuttled around several run-down hospitals.

(For a story on “Venezuelan girl’s diphtheria death highlights country’s health crisis”, click http://www.reuters.com/article/us-venezuela-health-idUSKBN15P1DA)

There were also 240,613 cases of malaria last year, up 76.4 percent compared with 2015, with most cases of the mosquito-borne disease reported in the rough-and-tumble Bolivar state.

Cases of Zika rose to 59,348 from 71 in 2015, reflecting the spread of the mosquito-borne virus around Latin America last year. There was no data for likely Zika-linked microcephaly, where babies are born with small heads, although doctors say there have been at least several dozen cases.

(To read the story on “Amid government silence, Venezuela’s microcephaly babies struggle”, click http://www.reuters.com/article/us-health-zika-venezuela-idUSKBN12H1NY)

(Reporting by Alexandra Ulmer; Editing by Girish Gupta and Frances Kerry)