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Scientists Find Protein To “Turbo-Charge” Immune System
Scientists at Imperial College London have found what they call a “game-changer” for cancer treatment: a protein that will “turbo-charge” the immune system to fighting cancers and viruses.
“This is exciting because we have found a completely different way to use the immune system to fight cancer,” said Professor Philip Ashton-Rickardt, from the Section of Immunobiology in the Department of Medicine at Imperial, who led the study.
“It could be a game-changer for treating a number of different cancers and viruses. This is a completely unknown protein. Nobody had ever seen it before or was even aware that it existed. It looks and acts like no other protein.”
When the body detects cancer, it will immediately flood the immune system with T-cells which fight the cancer. However, the body quickly reduces that output after the initial wave. The new protein creates T-cells in large enough numbers that cancer cannot fight them off.
The protein also creates “memory cells” in the immune system to recognize previously fought cancers and viruses to lessen the chances of their return.
“The discovery of a protein that could boost the immune response to not only cancer, but also to viruses, is a fascinating one,” Dr. Mike Turner of the Wellcome Trust, told the Daily Telegraph. “Further investigation in animal models is needed before human trials can commence, but there is potential for a new type of treatment that capitalizes on the immune system’s innate ability to detect and kill abnormal cells.”
The study has been published in the journal Science.