A major trial of a new vaccine to fight tuberculosis has ended in failure after researchers discovered it did not provide protection to infants exposed to the bacteria.

The trial is significant because the current vaccine, Bacillus Calmette-Guerin (BCG) is only partially effective against the bacteria. While the new vaccine, MVA85A, showed some boosting of the immune system in adults, it produced no reaction in infants who had been given BCG. Continue reading →