Doctors devise care plan for babies as Zika threat looms in U.S.

mosquito under microscope

By Julie Steenhuysen

CHICAGO (Reuters) – As U.S. public health officials try to determine whether Zika has arrived in the country, doctors are establishing guidelines on how to care for the rising number of babies whose mothers were infected with the virus during pregnancy.

Florida said it is investigating two possible cases of Zika not related to travel to an area where Zika is active, raising the possibility of the first incidence of local transmission of the mosquito-borne virus.

On Thursday, the Florida Department of Health said it was investigating a non travel-related case of Zika in Broward County, marking the second such case. Florida has asked the U.S. Centers for Disease Control and Prevention to assist in its investigation that must also rule out sexual transmission.

So far, 400 pregnant women in the continental United States have evidence of Zika infection, up from 346 from a week ago, the CDC reported on Thursday. All of those were related to travel or sex with an infected person who had traveled.

Three more babies have been born in the United States with birth defects linked to Zika infections in their mothers, bringing the total to 12, CDC said.

Zika has been proven to cause microcephaly, a severe birth defect marked by small head size and undersized brains that requires a complex network of care providers and social workers to treat and provide support to parents.

But microcephaly is just the tip of the iceberg, according to experts speaking at a CDC-sponsored workshop on Thursday. They said many babies exposed in utero who appear normal at birth may have developmental problems down the road, including hearing and vision problems.

For example, babies born without a functional sucking reflex may never develop the ability to swallow and will need to be fed through a feeding tube. These infants will have a higher risk of pneumonia, said Dr. Edwin Trevathan, a pediatrician and child neurologist at Vanderbilt University Medical Center.

Less obvious damage to structures on only one side of the brain may cause seizure disorders that do not appear until adolescence, Trevathan said.

Pediatric experts at the workshop are reviewing the potential consequences of Zika infection and plan to make recommendations on ways to treat Zika-exposed infants.

The connection between Zika and microcephaly first came to light last fall in Brazil, which has now confirmed more than 1,600 cases of microcephaly that it considers related to Zika infections in the mothers.

FLORIDA PROBE

The recommendations come as Florida officials investigate what may be the first cases of Zika in the continental United States caused by the bite of a local mosquito.

Florida officials will not elaborate on how a resident of Miami was infected and whether the first case under investigation was related to mosquitoes.

“We continue to investigate and have not ruled out travel or sexual transmission at this time,” Florida spokeswoman Mara Gambineri said in an email on Thursday. However, she said the state still suspects the case is not related to travel to a Zika-infected area.

The White House on Wednesday released a statement saying President Barack Obama had spoken to Florida Governor Rick Scott regarding a suspected case of mosquito transmission of Zika and promised more money to fight the virus.

At the Zika workshop, Dr. Marc Fischer, chief of surveillance and epidemiology activity at the arboviral diseases branch of the CDC, said the agency has worked with state health departments to establish strategies to identify possible local transmission in the United States.

“When and if there is a case of local transmission, we work with local health departments to identify additional cases to define the geographic scope of the outbreak,” he said.

That includes surveying households and neighbors within a 150-yard radius around the residence of the person who has Zika.

“That’s basically the flying radius of the vector mosquitoes,” he said.

According to the U.S. Zika response plan, Zika local transmission is defined as two or more cases not due to travel or sex with an infected person that occur in a one-mile diameter over the course of a month.

CDC has given Florida $2 million for Zika preparedness, and on Thursday awarded another $5.6 million to assist the state with Zika as part of an additional $60 million in Zika funds to states announced on Thursday. U.S. lawmakers so far have not approved any of the White House’s $1.9 billion request for Zika.

CDC plans to award another $10 million to states and territories on Aug. 1 to speed identification of microcephaly and other birth defects linked to Zika.

(Additional reporting by Bill Berkrot in New York; Editing by Bernard Orr)

First baby with Zika-related birth defect microcephaly born in Florida

Hillsborough County mosquito control drives through a neighborhood spraying against mosquitos

By Colleen Jenkins

(Reuters) – A Haitian woman in Florida has delivered the first baby in the state born with the birth defect microcephaly caused by the Zika virus, Florida’s health department said on Tuesday.

The mother contracted the mosquito-borne virus in her home country and traveled to Florida to give birth, state officials said in statements.

If confirmed by the U.S. Centers for Disease Control and Prevention, the child will be the fifth in the United States to be born with a birth defect linked with travel to a country in which Zika is circulating.

Another four pregnant women lost their babies as a result of travel-related Zika infections, according to the latest CDC report as of June 16. So far, there have not been any cases of Zika in the United States arising from local mosquito transmission.

The CDC’s U.S. Zika Pregnancy Registry does not specify the states where those cases occurred. Cases of babies with microcephaly previously were reported in Hawaii and New Jersey.

U.S. health officials have concluded that Zika infections in pregnant women can cause microcephaly, a birth defect marked by unusually small head size and potentially severe developmental problems.

The U.S. cases so far involve women who contracted the virus outside the United States in areas with active Zika outbreaks, or were infected through unprotected sex with an infected partner.

Health experts expect local transmission to occur in the United States as mosquito season gets underway, particularly in states such as Florida and Texas.

Florida Governor Rick Scott signed an executive order last week that allocated about $26 million for Zika preparation and response in the state. But in Washington on Tuesday, funding to battle the virus failed to advance in the U.S. Senate.

The connection between Zika and microcephaly first came to light last fall in Brazil, which has now confirmed more than 1,400 cases of microcephaly that it considers to be related to Zika infections in the mothers.

The World Health Organization has said there is strong scientific consensus that Zika also can cause Guillain-Barre, a rare neurological syndrome that causes temporary paralysis in adults.

(Reporting by Colleen Jenkins; Editing by Julie Steenhuysen and Bernard Orr)

U.S. researcher contracts Zika during experiement

Aedes aegypti mosquitoes are seen at the Laboratory of Entomology and Ecology of the Dengue Branch of the U.S. Centers for Disease Control and Prevention in San Juan

(Reuters) – A United States laboratory researcher was back at work after contracting the Zika virus by pricking herself with a needle during an experiment last month, broadcaster ABC News said on Thursday.

There is no vaccine or treatment for Zika, which is a close cousin of diseases such as dengue and chikungunya, and causes mild fever, rash and red eyes. An estimated 80 percent of those infected have no symptoms.

The unidentified researcher at the University of Pittsburgh pricked herself on May 23 and showed symptoms on June 1, returning to work five days later when she no longer had a fever, ABC News said, citing a statement from the school.

School officials were not immediately available for comment.

The incident was the fourth confirmed case of the Zika virus in Allegheny County, its health department said, without giving details of the accident.

“Despite this rare incident, there is still no current risk of contracting Zika from mosquitos in Allegheny County,” department director Karen Hacker said in a statement.

U.S. health officials have concluded that Zika infections in pregnant women can cause microcephaly, a birth defect marked by small head size that can lead to severe developmental problems in babies.

The World Health Organization has said there is strong scientific consensus that Zika can also cause Guillain-Barre, a rare neurological syndrome that causes temporary paralysis in adults.

The connection between Zika and microcephaly first came to light last fall in Brazil, which has now confirmed more than 1,400 cases of microcephaly that it considers to be related to Zika infections in the mothers.

To reduce the chance of virus transmission, the Pittsburgh researcher is using insect repellent to avoid mosquito bites, besides wearing garments with long sleeves and trousers, ABC News added.

(Reporting by Brendan O’Brien in Milwaukee; Editing by Clarence Fernandez)

Hawaii County declares state of emergency over dengue fever outbreak

The growing number of dengue fever cases in Hawaii County has prompted the county’s mayor to declare a state of emergency, a measure that aims to reduce the spread of the disease.

William P. Kenoi issued the declaration on Monday as the state Department of Health reported that there have been confirmed 251 cases of the mosquito-borne illness since last September.

All of the confirmed cases have been in Hawaii County, which is the state’s largest island.

Kenoi’s declaration allows people to dump tires at county landfills, which had been outlawed. The Centers for Disease Control and Prevention (CDC) says used tires can collect rain, making them a good place for mosquitos to lay eggs, and mosquito control is key to combating dengue.

Hawaii Governor David Y. Ige issued a statement saying he supported Kenoi’s emergency proclamation, but he would only declare a statewide emergency if certain conditions were met.

According to the World Health Organization (WHO), dengue fever usually triggers a flu-like illness that lasts up to a week. Symptoms include headaches, vomiting, muscle pains and rashes. In some cases, however, dengue can become severe and lead to potentially fatal complications.

The WHO says severe dengue causes about 500,000 hospitalizations and 12,500 deaths every year, though access to proper medical care significantly lowers the disease’s mortality rate.

Hawaii health officials have not reported any deaths as a result of this outbreak.

The Hawaii Department of Health says dengue isn’t usually found in Hawaii, but there have been some cases of infected travelers coming to Hawaii from areas where the disease is spread. But it says this outbreak is of locally-acquired dengue, the state’s first such event since 2011.

Dengue is different than the Zika virus, another mosquito-borne illness. However, both dengue and Zika can be transmitted by the Aedes aegypti mosquito and both have spread to new areas.

The WHO says dengue has reached more than 100 countries over the past 50 years, recording a 30-fold increase in its incidence. About half the world’s population is now at risk of infection.

The CDC has issued numerous travel warnings about the Zika virus, and the WHO recently deemed Zika an international public health concern as scientists investigate its potential connection to a rare birth defect called microcephaly that affects head size.

The Hawaii Department of Health has said that one Oahu child who was born with microcephaly had been infected with Zika, though his mother likely got infected when she was living in Brazil. The country saw a substantial rise in microcephaly last year.

Only about 20 percent of those infected with Zika show any symptoms, according to the CDC. Those symptoms include fever, rash and joint pain and most people fully recover within a week.