Approaching hurricane sparks runs in Hawaii on plywood, water and gasoline

Paul Akamine fills propane tanks for customers as Hurricane Lane approaches Honolulu, Hawaii, U.S. August 22, 2018. REUTERS/Hugh Gentry

By Sue Horton

HANALEI, Hawaii (Reuters) – Micco Godinez, who rents out kayaks on the island of Kauai and loves surfing, said he was twice tempted to hit the waves on Wednesday but kept his focus on a more pressing concern – getting ready to board up his home for a major hurricane.

With forecasts calling for Hurricane Lane to strike or brush past Hawaii’s “Garden Isle” on Friday, Godinez, 66, has joined tens of thousands of others on Kauai, and across the state, in the rituals of disaster preparation.

A long line of cars wait as people fill up their vehicles with gasoline as Hurricane Lane approaches Kauai, Hawaii, U.S., August 22, 2018. REUTERS/ Sue Horton

A long line of cars wait as people fill up their vehicles with gasoline as Hurricane Lane approaches Kauai, Hawaii, U.S., August 22, 2018. REUTERS/ Sue Horton

Lane, wavering between Category 4 and Category 5 strength on the five-step Saffir-Simpson hurricane scale, churned toward the U.S. Pacific island state with sustained winds of up to 155 miles per hour (250 kph) on Wednesday, as authorities urged residents to stock up on water, food and medicines.

Across Hawaii, jittery residents lined up at hardware centers, gasoline stations and grocery stores. But nowhere was the sense of urgency perhaps more palpable than on Kauai, where torrential rains four months ago triggered widespread flooding that destroyed homes and washed out roads.

“Some people here were just wiped out in that flood. It rained 50 inches (127 cm) in 24 hours,” said Hanalei resident Charlie Cowden, who owns several surf shops on the island. “Now there is this.”

Many older residents recalled even greater devastation from the last Category 4 storm to pummel Hawaii, Hurricane Iniki, which made landfall on Kauai in September 1992, killing six people and leveling or damaging more than 14,000 dwellings.

Luke Yamanuha loads plywood into his truck as Hurricane Lane approaches Honolulu, Hawaii, U.S. August 22, 2018. REUTERS/Hugh Gentry

Luke Yamanuha loads plywood into his truck as Hurricane Lane approaches Honolulu, Hawaii, U.S. August 22, 2018. REUTERS/Hugh Gentry

‘SLIM PICKINGS’

Godinez, who lives two blocks from the ocean in the bayside town of Hanalei on Kauai’s north shore, said he spent part of his day shopping for lumber and a recharging device for his portable drill.

He described the mood in town as “pleasantly apprehensive” and said he even felt the familiar pang of one of his favorite pastimes. “Twice the surf was up, and twice I wanted to go surfing, but I had other things pressing on my mind.”

He recalled getting up early to drive to a Home Depot building-supply outlet before it opened at 6 a.m., only to find two dozen others already lined up ahead of him.

“There’s a run on plywood,” he said. “It was slim pickings when I was there.”

Pausing later after filling up jugs of water, Godinez said he and his wife would spend the rest of the day taking measurements and cutting plywood to fit over more than 18 windows on their two-story house.

“Measure twice, cut once, and away we go,” he said, adding they would wait until Thursday for the latest forecasts before deciding whether to go ahead with fastening the boards to the windows.

Since Hanalei is on the opposite side of Kauai from where the hurricane is most likely to come ashore, Godinez said he was less concerned about ocean storm surge than ferocious winds.

Godinez said he, his wife and two guests planned to “hunker down” in a first-floor laundry room at the height of the storm, should it make landfall by late Thursday or early on Friday.

With two small laundry windows sealed up and probably no electricity, except for battery-powered flashlights, “It’s going to be hot and dark,” he said.

(Reporting by Sue Horton; Additional reporting and writing by Steve Gorman in Los Angeles; Editing by Bill Tarrant and Peter Cooney)

Iowa student’s murder thrust into U.S. debate over immigration

Cristhian Rivera, 24, accused of killing University of Iowa student Mollie Tibbetts, is led from the courtroom after making his initial appearance on a charge of first-degree murder during at the Poweshiek County Courthouse in Montezuma, Iowa, U.S., August 22, 2018. Jim Slosiarek/The Gazette/Pool via REUTERS

By Joseph Ax

(Reuters) – The arrest of a man who U.S. authorities have said is an illegal immigrant on charges of murdering an Iowa college student has thrust the case into the debate on immigration policy, with President Donald Trump blaming Mollie Tibbetts’ death on weak laws.

Christhian Rivera, 24, was arrested and charged on Monday with the murder of 20-year-old Tibbetts, who disappeared in July while out jogging. A woman’s body has been found but has not yet been positively identified, authorities have said.

Mollie Tibbetts of Brooklyn, Iowa, a college student who went missing, poses for an undated photograph obtained by Reuters August 22, 2018. Social Media via REUTERS.

Mollie Tibbetts of Brooklyn, Iowa, a college student who went missing, poses for an undated photograph obtained by Reuters August 22, 2018. Social Media via REUTERS.

Law enforcement officials told reporters on Monday that Rivera was Mexican and in the country illegally. However, his defense lawyer said in a court filing on Wednesday that Rivera had legal status.

Trump, who has taken a tough stance on immigration and referred to some Mexican migrants as criminals and rapists in his 2016 election campaign, made a reference to the Tibbetts case at a rally in West Virginia on Tuesday.

“Should never have happened,” said Trump. “The immigration laws are such a disgrace.”

The political fallout from the killing could reverberate across Iowa, a swing state that has a hotly contested gubernatorial race and where Democrats see a chance at taking two of the 23 seats they need to win back from Republicans in November’s midterms to gain a majority in the House of Representatives.

Iowa Republican Governor Kim Reynolds echoed Trump’s approach, blaming Tibbetts’ death on the nation’s immigration laws.

“We are angry that a broken immigration system allowed a predator like this to live in our community, and we will do all we can bring justice to Mollie’s killer,” she said in a Tuesday statement.

But Republican members of Congress and congressional candidates in closely competitive Iowa districts were more guarded, perhaps wary of voter backlash if they politicized the case.

Republican lawmakers Rod Blum and David Young each issued statements expressing sympathy for the Tibbetts’ family but avoided any mention of illegal immigration.

Christopher Peters, a Republican mounting a long-shot challenge to Iowa Democratic Congressman Dave Loebsack, said on Facebook that politicizing Tibbetts’ murder “cheapens the death of this young woman.”

“Yes, our immigration system is broken, and Congress has failed to fix it,” Peters wrote. “There is much we can and must do. For now, though, we should mourn the loss of Mollie.”

Tibbetts’ father, who made many public pleas for information about his daughter’s whereabouts, could not be reached for comment on Wednesday. A man who picked up the phone at the home of Tibbetts’ mother in Iowa declined to comment.

During his 2016 campaign, Trump spoke almost daily about the 2015 death of Kate Steinle, who was struck by a bullet that ricocheted off the ground after being accidentally fired by an illegal immigrant. A jury last year cleared the immigrant of murder and manslaughter charges, and Trump railed against the decision.

Iowa voters might recoil at Tibbetts’ death being politicized so quickly, said Timothy Hagle, a political science professor at the University of Iowa.

“Kate Steinle was used nationally by Republicans as an example of a system that needs fixing,” Hagle said. “That might happen again, but I’m not sure it will be handled the same way in Iowa.”

Several residents of Brooklyn, Iowa, where Tibbetts lived, expressed sadness at how quickly her death had become a political talking point.

“I wish Trump had not made this political,” said Janice, a 60-year-old waitress at the Classic Deli, who declined to give her last name. “The family just wants to heal. I have a farm with Mexican immigrants, and I never felt afraid.”

(Reporting by Joseph Ax in New York, additional reporting by John Peragine in Brooklyn, Iowa and Ginger Gibson in Washington; Editing by Scott Malone and Rosalba O’Brien)

Illusory to think Syrian refugees can return now, France says

FILE PHOTO: A general view shows refugee tents erected at the Syrian side of the Israeli-Syrian border as it is seen from the Israeli-occupied Golan Heights, Israel July 19, 2018. REUTERS/Amir Cohen -/File Photo

PARIS (Reuters) – France dismissed on Thursday any suggestion that millions of Syrian refugees could start returning home, as urged by Russia, which backs President Bashar al-Assad.

Foreign ministry spokeswoman Agnes von der Muhll said the conditions for a return have not been met, given Assad’s treatment of those who have already gone home and a possible offensive on rebel territory in northern Syria.

In recent weeks Russia has called on Western powers opposed to the Syrian government to help refugees return home and aid reconstruction of areas under his control.

However, Von der Muhll cited a decree depriving refugees and internally displaced people of their properties, the instability of the country and cases of arrest and forced conscription of Syrians returning from Lebanon.

“To consider a return of the refugees is illusory, in the current conditions,” she said.

The seven-year civil war has killed an estimated half a million people, driven 5.6 million out of Syria and displaced around 6.6 million within the country.

Most refugees are from the Sunni Muslim majority, and it is unclear whether Assad’s Alawite-dominated government will allow all to return freely or whether they would want to. Sunnis made up the bulk of the armed opposition to Assad.

France, which backs the opposition, says it will not support reconstruction of areas under Assad’s control until there is a negotiated political transition under U.N. auspices.

“This year has seen the largest movement of displaced people since the beginning of the conflict and … the entire international community has warned of the risks of a major humanitarian and migratory crisis in the event of an offensive against the province of Idlib,” Von der Muhll said.

The Idlib region, a refuge for civilians and rebels displaced from other areas of Syria as well as jihadist forces, was hit by air strikes and shelling last week, in a possible prelude to a full-scale government offensive.

(Reporting by John Irish; editing by David Stamp)

Pope to visit a changed Ireland during ‘perfect storm’ of abuse crises

A boy gestures as he rides on a truck with wax work figures of Pope Francis and former Pope John Paul II in Dublin, Ireland August 23, 2018. REUTERS/Hannah McKay

By Philip Pullella and Padraic Halpin

VATICAN CITY (Reuters) – When Pope John Paul II made the first visit by a pontiff to Ireland in 1979, contraception and divorce were still illegal and the Catholic Church’s influence on a deeply conservative society was near-total.

Pope Francis, who arrives in Dublin on Saturday for a two-day visit, will find an Ireland his predecessor would not have recognized as Catholic.

Ireland is now led by a gay prime minister. Three years ago, it became the world’s first country to adopt gay marriage by popular ballot. Last May, it ended one of the West’s strictest abortion regimes. Both referendums won by large majorities despite Church opposition.

And he will find a wounded Church whose once-absolute authority has been laid low by sexual abuse scandals.

Weekly Mass attendance was at about 80 percent 40 years ago. It’s about 35 percent now, and last year only half of marriages were held in religious ceremonies in churches.

The rock that was once Irish Catholicism began crumbling in the late 1990s, with media investigations about the notorious Church-run, and government-backed, Magdalene Laundries, where “fallen women” were forced to work in slave-like conditions.

A series of official government inquiries between 2005 and 2014 exposed sexual abuse of minors by priests in various areas of Ireland. Church homes for unmarried mothers have been investigated for their treatment of children.

“When the pope arrives in Ireland this weekend, he will find a Catholic Church not just falling to ruin, but in some respects beyond repair,” wrote Fintan O’Toole, a columnist for the Irish Times.

“He will be greeted with joy by the faithful, but few, even among them, will expect him to be able to fix an institution that has been shaken to its very foundations,” he wrote.

A “PERFECT STORM” OF ABUSE CRISES

Francis could not be visiting Ireland at a worse time.

Recent sexual abuse crises in the United States, Chile, and Australia have reminded the Irish people of their scandals at home and fed escalating anger towards bishops who mishandled abuse cases.

One Vatican official called the combination “a perfect storm”.

Last week, a grand jury in the U.S. state of Pennsylvania released the findings of the largest-ever investigation of sex abuse in the U.S. Church, finding that 301 priests in the state had sexually abused minors over the past 70 years.

The damning U.S. report has given Irish abuse victims and their advocates from around the world – some have flown into Dublin for the visit – fresh resolve to demand that the pope do more to root out sexual abuse in the Church.

“There are those who feel they can no longer trust our message, perhaps because they have been directly hurt and betrayed in their families by their experience of Church, or because the revelations of such heinous crimes have shocked them to the core,” said Archbishop Eamon Martin, Ireland’s most senior Church official.

The main purpose of the pope’s trip is to close a week-long international Catholic gathering on the theme of the family that takes place every three years in a different city.

In one sign of just how much sexual abuse has cast a shadow on a meeting that was to have concentrated on family themes, Martin delivered the gathering’s keynote address in place of Cardinal Donald Wuerl of Washington D.C., who withdrew after he was criticized in the Pennsylvania report.

Abuse victims, their families, and supporters will gather in another part of Dublin while the pope says Mass on Sunday. Many of them have called on him to do more than just hold a private meeting with a select group of survivors.

A silent vigil will be held at the same time by locals in the western town of Tuam. Four years ago, an unmarked grave with the remains of hundreds of babies was found there, on the grounds of a former Church-run home for unwed mothers and their children, shocking the country once more.

One sign of the Church’s waning influence, if any were needed, can be seen in Dublin’s city center, where street vendors like Marion White are struggling to sell papal flags and T-shirts made especially for the visit.

“I worked here for the pope in 1979 and the country was electrified. It was an amazing event. Everyone was so cheery and happy,” said White, who has worked the stall near Dublin’s main thoroughfare of O’Connell Street since he was nine-years old.

“It’s all changed now, with all that has happened,” he said. “There’s a lot of controversy, and people are not afraid to say it to us.”

(Additional reporting by Padraic Halpin and Graham Fahy in Dublin, editing by Larry King)

Venezuelans entering Ecuador illegally receive help to reach Peru

Venezuelan migrant Plaza Pernia family hug as they arrive from the northern city of Tumbes, border with Ecuador, to the bus terminal in Lima, Peru August 22, 2018. REUTERS/Guadalupe Pardo

QUITO (Reuters) – Some 250 Venezuelans who illegally entered Ecuador to join tens of thousands fleeing a crisis at home have won safe passage to the Peruvian border, a few days before Peru’s government tightens its migration requirements.

Ecuadorean authorities said on Wednesday they had dispatched buses to take the migrants 840km from the Andean country’s northern border with Colombia to the Huaquillas coastal crossing with Peru.

This year 423,000 Venezuelans have entered Ecuador through the Rumichaca border, many planning to continue south to find work in Peru. Alarmed, Ecuador last Saturday put in place rules requiring Venezuelans to show passports, rather than just national identity cards. Peru will do the same beginning on Saturday.

Hundreds of migrants who began traveling days ago by bus and on foot through Colombia from Venezuela before the policy change crossed the Rumichaca checkpoint on Tuesday. They set out to walk and hitchhike, often in freezing conditions, to Huaquilla.

Maly Aviles, a 26-year-old Venezuelan, spent days on the Ecuador-Colombia border waiting with friends for a solution before the buses arrived.

“There is no way back. To return to Venezuela is suicidal,” she said.

Venezuela’s economy has been in steep decline and there are periodic waves of protests against the socialist government of President Nicolas Maduro. Maduro argues that he is the victim of a Washington-led “economic war” designed to sabotage his administration through sanctions and price-gouging.

The chaos has forced many to flood across the borders in search of work, food, and basic healthcare. This has stretched social services, created more competition for low-skilled jobs and stoked fears of increased crime.

The governor of Ecuador’s northern Pichincha province said more transfers would be organized for Venezuelans in the coming days.

“The Venezuelans have taken the decision to head for Peru and in Ecuador we must guarantee their rights. It’s a humanitarian crisis,” he told a local radio station.

(Reporting by Daniel Tapia; Writing by Angus Berwick; Editing by Leslie Adler)

Hurricane Lane threatens direct hit on Hawaii, churns toward Oahu

A photo taken from the International Space Station and moved on social media by astronaut Ricky Arnold shows Hurricane Lane in the early morning hours near Hawaii, U.S., August 22, 2018. Courtesy @astro_ricky/NASA/Handout via REUTERS

y Jolyn Rosa

HONOLULU (Reuters) – Hurricane Lane, threatening a direct hit as Hawaii’s worst storm in a quarter century, on Thursday churned toward Oahu, the island with the largest population, as schools, government offices, and business closed and residents stocked up on supplies.

Packing sustained winds of up to 130 miles per hour (215 km per hour), Lane could dump 10 to 20 inches (25-50 cm) of rain, triggering flash floods and landslides, the National Weather Service (NWS) said. More than 30 inches could fall in some places, it said.

“Preparations to protect life and property should be rushed to completion,” the NWS Central Pacific Hurricane Center in Honolulu said in an advisory.

As of early Thursday, Lane was centered about 210 miles (335 km) south-southwest of Kailua-Kona, a town on the west coast of the Big Island, the NWS said. It was classified as a powerful Category 4 storm on the five-step Saffir-Simpson scale of hurricane strength.

The NWS said the storm weakened slightly overnight but excessive rainfall would affect the Hawaiian islands into the weekend, “leading to significant and life-threatening flash flooding and landslides.”

More than a foot of rain has already fallen on part of the Big Island, the NWS said on Thursday morning.

The center also warned of “very large and damaging surf” along exposed west- and south-facing shorelines, likely leading to significant coastal erosion.

A hurricane warning was in effect for Oahu, Maui County, and Hawaii County. The islands of Kauai and Niihau remained on hurricane watch and could face similar conditions starting Friday morning.

Governor David Ige has urged residents to take the threat seriously and prepare for the worst by setting aside a 14-day supply of water, food, and medicines.

All public schools, University of Hawaii campuses and nonessential government offices on the islands of Oahu and Kauai will be closed for at least two days starting on Thursday, Ige said Wednesday.

The shelves of a downtown Honolulu Walmart were stripped of items ranging from canned tuna to dog food as well as bottled water and coolers full of ice after warnings of possible power outages.

“I went to Safeway last night for regular groceries. Everyone was in a panic,” said Thao Nguyen, 35, an employee at a Honolulu branch of Hawaiian shirt retailer Roberta Oaks.

Long lines of cars formed at gasoline stations in Honolulu and people pulled small boats from the water ahead of the expected storm surge. U.S. Navy ships and submarines based in Hawaii were instructed to leave port, a common practice when a hurricane approaches to avoid damage.

President Donald Trump declared a state of emergency for Hawaii and ordered federal authorities to help supplement state and local responses, the White House said on Thursday.

The most powerful hurricane on record to hit Hawaii was Category 4 Iniki, which made landfall on Kauai island on Sept. 11, 1992, according to the National Oceanic and Atmospheric Administration. It killed six people and damaged or destroyed more than 14,000 homes.

(Additional reporting by Gina Cherelus in New York, Brendan O’Brien in Milwaukee, Doina Chiacu in Washington, and Steve Gorman and Dan Whitcomb in Los Angeles; Editing by Jeffrey Benkoe and Marguerita Choy)

Islamic state chief, in rare speech, urges followers to persevere

FILE PHOTO: A man purported to be the reclusive leader of the militant Islamic State Abu Bakr al-Baghdadi making what would have been his first public appearance, at a mosque in the centre of Iraq's second city, Mosul, according to a video recording posted on the Internet on July 5, 2014, in this still image taken from video. REUTERS/Social Media Website via Reuters TV/File Photo

CAIRO (Reuters) – Islamic state leader Abu Bakr al-Baghdadi, in his first purported speech in nearly a year, has called on followers to persevere, according to a statement posted on the group’s media outlet.

“For the Mujahideen (holy warriors) the scale of victory or defeat is not dependant on a city or town being stolen or subject to that who has aerial superiority, intercontinental missiles or smart bombs,” Baghdadi said in a recording posted on his al-Furqan media group.

Reuters was unable to verify whether the voice on the recording was Baghdadi’s.

Islamic State, which until last year controlled large areas in Syria and Iraq, has since been driven into the desert following successive defeats in separate offensives in both countries.

Baghdadi, who declared himself ruler of all Muslims in 2014 after capturing Iraq’s main northern city Mosul, is now believed to be hiding in the Iraqi-Syrian border region after losing all the cities and towns of his self-proclaimed caliphate.

The secretive Islamic State leader has frequently been reported killed or wounded since leading his fighters on a sweep through northern Iraq. His whereabouts are not known but Wednesday’s message appears to suggest he is still alive.

One of his sons was reported to have been killed in the city of Homs in Syria, the group’s news channel reported earlier this year.

Baghdadi’s last message came in the form of an undated 46-minute audio recording, released via the al-Furqan organization in September, where he urged followers across the world to wage attacks against the West and to keep fighting in Iraq, Syria and elsewhere.

(Reporting by Ali Abdelaty, writing by Sami Aboudi; editing by David Stamp)

Toxin at heart of drug recall shows holes in medical safety net

FILE PHOTO: The headquarters of the European Medicines Agency (EMA), is seen in London, Britain, April 25, 2017. REUTERS/Hannah McKay -/File Photo

By Alexandra Harney and Ben Hirschler

SHANGHAI/LONDON (Reuters) – A toxin inadvertently produced in the manufacture of a widely prescribed medicine but not spotted for years raises questions about regulators’ ability to detect risks in a sprawling global drug supply chain increasingly reliant on factories in China.

China’s Zhejiang Huahai Pharmaceutical, which produces bulk ingredients for drugmakers, told its customers in late June it had found NDMA in its valsartan, an off-patent blood pressure drug originally developed by Novartis.

The discovery means that some of the 10 billion pills containing valsartan sold worldwide last year to prevent heart attacks and strokes had traces of N-nitrosodimethylamine (NDMA), classified as a probable human carcinogen. No one has been reported as sickened by the toxin, once used in the production of liquid rocket fuel.

Regulators and industry experts say the toxin almost certainly was introduced when Huahai changed the way it produced valsartan in 2012 – a modification that was signed off on by the European body that sets standards. Subsequent inspections by European, U.S., and Chinese regulators also found no problem.

“Everyone failed – the company, the inspectors, the FDA (U.S. Food and Drug Administration), the Europeans, the Chinese,” said Philippe André, an independent pharmaceutical auditor who inspected two Huahai facilities last August and found no critical concerns. “It’s a system failure.”

Reuters was unable to determine how Huahai first discovered the problem. In a July 7 statement released through the Shanghai Stock Exchange, it said it detected the toxin during the “optimization and evaluation” of its manufacturing process.

A Novartis spokesman told Reuters that its generic drugs arm, Sandoz, spotted the NDMA in the course of intensive testing to prepare for expanding its purchases of valsartan. He declined to comment further, including on the identity of the manufacturer or when the tests took place.

Two other smaller bulk suppliers – Zhejiang Tianyu Pharmaceutical and a unit of India’s Hetero Drugs – have since also discovered traces of NDMA in some of their valsartan.

The three companies declined to comment to comment about the case.

REDUCE WASTE

Huahai said in a document released through the Shanghai Stock Exchange it changed the production process to reduce waste and improve yields.

“The NDMA impurity was produced in trace amounts during the normal manufacturing process according to the company’s current registered process,” it said in a statement on July 24.

“All changes in the company’s valsartan manufacturing process have been approved by each country’s drug regulator, and the company manufactures in compliance with legal and regulatory standards.”

The European Medicines Agency (EMA) regulator, which first publicly raised the alarm in a statement on July 5, told valsartan suppliers in a subsequent memo dated July 16 that the NDMA may have been connected to the combined use of the solvent dimethylformamide and sodium nitrite.

The FDA is also going on that hypothesis, said Janet Woodcock, director of its Center for Drug Evaluation and Research. She stressed the investigation was still going on.

“This (NDMA) was not what you look for in an inspection,” Woodcock said in an interview. “If you don’t test for this you’re not going to have an idea that it’s in there, and you’re not going to see it on an inspection.”

The European Directorate for the Quality of Medicines (EDQM), responsible for setting manufacturing standards, told Reuters it was aware the solvent was being used when it approved the changed process, but that NDMA as a by-product was unexpected and not tested for.

Detecting NDMA would have required gas chromatography coupled with mass spectrometry, a very sensitive level of testing, an EDQM spokeswoman said.

“These techniques are not normally used routinely to test pharmaceutical products,” she said.

RECALLS

Built by Novartis into the $6 billion-a-year brand Diovan, valsartan’s European and U.S. patents expired in 2011 and 2012.

Global sales totaled 10.4 billion pills last year, including combination products, healthcare data consultancy IQVIA estimates. People with high blood pressure typically take one pill daily and heart failure patients two.

More than 50 companies around the world making finished tablets from the tainted valsartan have recalled products in recent weeks, according to a Reuters analysis of national medicines agencies’ records. They include major generic drug manufacturers such as Teva Pharmaceutical Industries, Ranbaxy Laboratories, and Sandoz.

Based on the average NDMA impurity detected at Huahai of 60 parts per million (ppm), the EMA says there could be one additional case of cancer in every 5,000 people taking the highest dose for seven years.

The contamination puts a spotlight on manufacturers in China and India, which supply more than two-thirds of all active pharmaceutical ingredients used in medicines, industry executives estimate. China accounts for the lion’s share.

Huahai, founded in 1989 and listed in Shanghai in 2003, was one of the first Chinese companies to get drugs approved in the U.S. market.

The FDA has inspected the site that made the contaminated valsartan three times since 2010, its records show. European inspectors also visited regularly.

The provincial branch of the Chinese FDA (CFDA) also inspected Huahai facilities 10 times in connection with new drug applications between January 2016 and June 2018, the national online database shows.

SCRUTINY

U.S. and European regulators have increased scrutiny of Chinese and Indian drug factories after the adulteration of the blood thinner heparin sickened hundreds and caused the deaths of at least 81 Americans in 2007 and 2008.

The CFDA is also on alert.

Last month, it revealed that Changsheng Bio-technology , a vaccine maker, had fabricated data and sold ineffective vaccines for children. It also found that a diphtheria, tetanus and pertussis vaccine sold by the state-owned Wuhan Institute of Biological Products was substandard.

The fact that international inspections do not appear to have detected the NDMA contamination alarms Anders Fuglsang, a former European medicines regulator who runs a pharmaceutical consultancy in Denmark.

“We need to ask ourselves how it is possible – despite pharmacopoeias and agency guidelines, inspection programs with coordination across continents, a system of public quality control, and companies complying with all rules – that a nasty carcinogen can find its way into our drugs and be there for years without anyone noticing,” he said.

(Additional reporting by Shanghai newsroom, Zeba Siddiqui in Mumbai and Sharnya G in Bengaluru; Editing by Sonya Hepinstall)

Global wheat supply to crisis levels; big China stocks won’t provide relief

FILE PHOTO: Arnaud Caron, a French farmer drives an old Mc Cormick F8-413 combine as he harvests his last field of wheat, in Vauvillers, northern France, July 23, 2018. REUTERS/Pascal Rossignol

By Nigel Hunt

LONDON (Reuters) – A scorching hot, dry summer has ended five years of plenty in many wheat producing countries and drawn down the reserves of major exporters to their lowest level since 2007/08, when low grain stocks contributed to food riots across Africa and Asia.

Although global stocks are expected to hit an all-time high of 273 million tonnes at the start of the 2018/19 grain marketing season, according to U.S. Department of Agriculture estimates, the problem is nearly half of it is in China, which is not likely to release any onto global markets.

Experts predict that by the end of the season, the eight major exporters will be left with 20 percent of world stocks – just 26 days of cover – down from one-third a decade ago.

The USDA estimates that China, which consumes 16 percent of the world’s wheat, will hold 46 percent of its stocks at the beginning of the season, which starts around now, and more than half by the end.

The 126.8 million tonnes China is estimated to hold is up 135 percent from 54 million five years earlier.

“People need to get rid of China stocks (in their calculations) … if you do that, it’s just exceptionally tight,” said Dan Basse, president of AgResource Co in Chicago.

A repeat of the 2007/2008 crisis, which forced many countries to limit or ban exports, is unlikely in the absence of other drivers at the time, including $150-per-barrel crude oil.

The recent three-year high for wheat prices of $5.93 a bushel on the Chicago Board of Trade pales in comparison to the high of $13.34-1/2 a bushel in February 2008.

Importers in North Africa also appear to be better placed this time, with higher stocks of their own.

“It could have an impact on food inflation but in North African countries they have a good crop this year, fortunately, so their reliance is not as big as in the past years,” said Abdolreza Abbassian, chief economist at the United Nations’ Food and Agriculture Organisation (FAO).

“I don’t think we want to be alarmist in terms of consequences,” he added.

China started stockpiling wheat in 2006, setting a guaranteed floor price to ensure food security and stability.

At around $9.75 a bushel as of last week, Chinese prices are now so high that they cannot sell internationally without incurring a major loss.

Rabobank analyst Charles Clack said he expected China to continue to build stocks into next year but in the long-term, it would look to reduce reserves by curbing domestic production, reducing imports or conducting internal auctions.

“It will be a slow process … I wouldn’t expect exports to come flying out anytime soon,” he said.

Government wheat reserves now total nearly 74 million tonnes, according to Shanghai JC Intelligence Co Ltd, most of it from 2014-2017 but a small amount as old as 2013.

Sylvia Shi, analyst at JC Intelligence, said China would continue to import wheat it cannot produce in sufficient volumes to help meet a growing appetite for high-protein varieties for products like bread and other baked products as diets become Westernised.

DROUGHT

The wheat crop in several of the world’s biggest exporters – Argentina, Australia, Canada, the European Union, Kazakhstan, Russia, Ukraine and the United States – has suffered this year.

A spring drought in the Black Sea bread baskets Russia and Ukraine was swiftly followed by a summer heatwave in the European Union. Dry weather now also threatens crops in another important exporter, Australia.

Evidence of the serious harm done has grown as harvesting progresses.

Forecasts for the 28-member European Union have repeatedly been cut, with Germany set for its lowest grain harvest in 24 years after crops wilted under the highest summer temperatures since records began in 1881.

Russia’s agriculture ministry held a meeting with grain traders on Friday to discuss export volumes.

The ministry denied export limits were discussed but traders, some of whom were at the meeting, said curbs might be imposed later in the season following complaints from domestic meat producers about the rising cost of animal feed.

The United States is best placed to capitalize on a shortfall in global supply, with much higher stocks than rival exporters and rising production.

The outlook provides a much-needed boost for U.S. farmers caught in the crossfire of a trade war with China, a huge importer of U.S. soybeans and corn, as well as Mexico and Japan, two of the top buyers of U.S. wheat.

“The winner in the long term is the U.S. as they should get some demand flow back to them. It has been several years since we have seen the U.S. be in a position to get demand,” said Matt Ammermann, a commodity risk manager with INTL FCStone.

The Black Sea and Europe look set to lose market share, Ammermann said.

Canada, one of the world’s biggest high-quality wheat exporters, is expected to enjoy bigger yields than last year, according to a recent crop tour. But patchy rains have left crops highly variable across the western provinces.

“We don’t have a bin-buster coming. I just don’t see how we can push exports too much higher,” said Paterson Grain trader Rhyl Doyle.

SOUTHERN RESPONSE

The two major wheat exporters in the southern hemisphere, Argentina and Australia, are still months away from harvest.

A record crop is forecast in Argentina but production in Australia is expected to fall to the lowest level in more than a decade due to drought across the east coast.

Francisco Abello, who manages 7,000 hectares of land in western and north-central Buenos Aires province, said he and other growers are out to take advantage of high prices by investing in fertilizers to increase yields.

“We are having a great start to the season,” Abello said. “The ground was moist at planting time. Then it was cold and dry, which are the best conditions for the early wheat growing season.”

The Buenos Aires Grains Exchange has a preliminary wheat harvest estimate of 19 million tonnes, above what it says is the current record of 17.75 million tonnes.

In Australia, the outlook is less rosy. Analysts said production could fall below 20 million tonnes for the first time since 2008, although it is still likely to be well in excess of that year’s crop of just 13 million tonnes.

“The west of the country is looking good so the largest producing region could produce a crop in excess of 9 million tonnes alone. That may keep the headline number up,” said Phin Ziebell, an agribusiness economist at the National Australia Bank. “But with dry weather reducing output on the east, it could reduce exports nationally.”

(Additional reporting by Julie Ingwersen in Chicago, Dominique Patton and Hallie Gu in Beijing, Rod Nickel in Winnipeg, Sybille de La Hamaide and Valerie Parent in Paris, Hugh Bronstein in Buenos Aires and Colin Packham in Sydney; Graphics by Amanda Cooper; Editing by Veronica Brown and Sonya Hepinstall)

Powerful quake hits Venezuela coast, damage limited

People gather in the street after an earthquake in Caracas, Venezuela August 21, 2018. REUTERS/Marco Bello

By Alexandra Ulmer and Deisy Buitrago

CARACAS (Reuters) – A major earthquake of magnitude 7.3 struck Venezuela’s eastern coast, home to largely poor fishing communities, on Tuesday afternoon, shaking buildings as far away as Colombian capital Bogota and knocking power out in parts of Trinidad.

But the quake’s depth – 76.5 miles (123 km) below the surface – appeared to have mitigated the damage.

Venezuelan officials said there were no immediate reports of injuries and two sources at state oil company PDVSA [PDVSA.UL] told Reuters the OPEC member’s refineries and oil fields were operating normally. PDVSA did not immediately comment.

Venezuela is not in a good shape to deal with a natural disaster. It is already wrestling with a crippling economic crisis with medicine running short, hospitals barely able to function and some severe shortages of basics such as chicken and milk.

The tremor – one of the country’s strongest ever – hit at 5.31 p.m. (2131 GMT). Along Venezuela’s picturesque palm tree-dotted northern coast, residents said the long quake was terrifying and frightened people into dashing into the streets.

“I had gotten into bed to watch the news on TV and my bed started to move as if it was made of water,” said Elia Sanchez, a doctor in Cumana, the capital of the eastern state of Sucre that was the closest to the coastal epicenter. “We had to go down nine floors, it felt like it would never end.”

Rosymer Rodriguez, also in Cumana, said she could not see any significant damage but that people were still fearful.

“There are still people in the street. There are people packing bags in case there are aftershocks,” said Rodriguez.

Damage in Caracas was limited, but the quake did tilt the top five floors of an abandoned 45-story skyscraper known as the ‘Tower of David’, Interior Minister Nestor Reverol said.

The tower, originally intended to be a bank center but abandoned since 1994 and later occupied by squatters for years, dominates Caracas’ skyline. It features in the U.S. television spy drama “Homeland”. Pictures after the quake showed the building’s top floors, which are unfinished, leaning sideways.

Out east, the governor of Sucre called for calm.

“Do not fall victim to psychological terror, messages about a tsunami and all that,” said governor Edwin Rojas, who belongs to President Nicolas Maduro’s Socialist Party.

The Information Ministry did not respond to a request for comment for additional information.

People stand on the street after hearing an earthquake alarm in Bogota, Colombia Agust 21, 2018. REUTERS/Luisa Gonzalez

People stand on the street after hearing an earthquake alarm in Bogota, Colombia Agust 21, 2018. REUTERS/Luisa Gonzalez

ANDES, CARIBBEAN HIT

The quake was felt in capital Caracas, neighboring Colombia and nearby island nations like Trinidad and Tobago, and St. Lucia, to the west and north.

In Trinidad and Tobago, there were initial reports of some cracks to buildings, cars damaged when concrete debris fell on them, and loss of electricity. Traffic jams formed on highways in Port of Spain, but there were no immediate reports of casualties there either.

Colombia’s government said the country was unharmed too, although workers dashed out of high-rise blocks in the mountainous capital Bogota.

“It was a moment of panic, we thought the worst,” said Jimena Valencia, a 29-year-old administrator in the north of Bogota.

The U.S. Pacific Tsunami Center canceled an earlier warning of a possible tsunami along the coast near the epicenter, some 190 kilometers (118 miles) from Cumana.

United States Geological Survey geophysicist Jessica Turner said the quake’s depth would have dampened some of the shaking.

“A 7.3 magnitude quake is going to cause some damage, particularly as in this area, structures are vulnerable. The Earth is able to absorb some of the energy, but a 7.3 quake produces a lot of energy,” she said by telephone.

(Additional reporting by Vivian Sequera, Brian Ellsworth, Shaylim Castro, Corina Pons and Mayela Armas in Caracas, Sandra Maler in Washington, Helen Murphy in Bogota, Linda Hutchinson-Jafar in Port of Spain, and Marianna Parraga in Mexico City; Writing by Alexandra Ulmer; Editing by Peter Cooney, Rosalba O’Brien and Sandra Maler)